| Cat# | DIA-792 |
| Descriptions | Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) initiates mucin-type O-glycosylation by transferring N-acetylgalactosamine to serine or threonine residues of polypeptide substrates, exhibits broad substrate specificity, and is responsible for the initial step of O-linked glycan biosynthesis in most tissues. |
| Applications | Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) is suitable for O-glycan initiation detection kits and mucin-type glycosylation assay reagent development. |
| Enzyme Commission Number | EC 2.4.1.41 |
| Enzyme Source | Trichoplusia ni, High Five (baculovirus)-derived human Polypeptide Gal Nac Trans. |
| Reaction | L-seryl-[protein] + UDP-N-acetyl-alpha-D-galactosamine = 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + H+ + UDP |
| Activity Definition | Measured by its ability to transfer GalNAc from UDP-GalNAc to peptide EA2 . |
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