| Cat# | DIA-795 |
| Descriptions | Polypeptide N-acetylgalactosaminyltransferase 12 (GALNT12) is predominantly expressed in gastrointestinal tract tissues, mediates O-glycosylation of intestinal mucins, maintains mucosal barrier function, and is associated with colorectal cancer development and progression. |
| Applications | Polypeptide N-acetylgalactosaminyltransferase 12 (GALNT12) serves as a raw material for gastrointestinal mucin glycosylation detection kits and mucosal barrier assay reagent development. |
| Enzyme Commission Number | EC 2.4.1.41 |
| Enzyme Source | CHO-derived |
| Reaction | L-seryl-[protein] + UDP-N-acetyl-alpha-D-galactosamine = 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + H+ + UDP |
| Activity Definition | Measured by its ability to transfer GalNAc from UDP-GalNAc to peptide EA2 . |
| Download Datasheet: |  |
