Products

Lipid Metabolism Diagnostic Enzymes

Lipid-related assays use coordinated enzyme reactions for total cholesterol, triglycerides, non-esterified fatty acids (NEFA), lipoprotein-associated cholesterol, and total bile acids. Representative components include cholesterol esterase, cholesterol oxidase, lipases, glycerol kinase, glycerol-3-phosphate oxidase, and acyl-CoA enzymes.

Clinical Chemistry & General Metabolic Testing Enzymes

Clinical chemistry assays use oxidoreductases, hydrolases, transferases, and auxiliary enzymes to measure metabolites or enzyme activities. Products can support endpoint, fixed-time, kinetic, microplate, and automated analyzer workflows.

Diabetes and Blood Glucose Testing Enzymes

Glucose testing may use glucose oxidase, glucose dehydrogenase, or hexokinase-based systems. Selection depends on oxygen dependence, cofactor requirements, substrate specificity, signal chemistry, and the intended analyzer or sensor format.

Renal Function Diagnostic Enzymes

Renal testing may incorporate enzyme systems for creatinine, uric acid, and other metabolic measurements. Product selection should consider the complete reaction cascade, specimen matrix, calibration, and analyzer conditions.

Pancreatic Function Diagnostic Enzymes

Pancreatic and digestive enzyme assays can involve amylase, lipase, and related reaction components. These products support activity assays and coupled analytical methods, with method-specific attention to substrates, cofactors, and reaction conditions.

Liver Function Assay Enzymes

Liver-related testing includes catalytic activity assays for enzymes such as ALT, AST, ALP, GGT, and LDH, as well as enzymatic methods for selected metabolites. Reagent components should be matched to the analytical method and specimen matrix.

POCT and Biosensor Enzymes

Enzymes used in point-of-care and biosensor formats must be compatible with immobilization, electrode or sensor materials, sample matrices, and the intended storage format. Common applications include glucose, lactate, and cholesterol detection.

Cardiac and Muscle Injury Assay Enzymes

Enzymatic systems can support measurements of cardiac and muscle-associated markers, including catalytic activity methods and coupled detection reactions. Selection depends on the analyte, assay principle, and required analytical range.

Electrolyte and Small Metabolite Testing Enzymes

Enzymatic methods can support selected small-metabolite measurements and coupled reaction systems used alongside electrolyte and metabolic testing. Performance should be evaluated in the intended matrix and instrument configuration.

Enzymes for Environmental Monitoring

Enzyme-based analytical systems can support detection of selected environmental contaminants and chemical indicators. Application-specific performance depends on substrate specificity, matrix effects, pH, temperature, and the field or laboratory detection format.

Enzymes for Food Safety Testing

Enzymatic reagents can support food testing for selected chemical indicators, substrates, and contaminants. Suitable enzyme systems depend on the target, sample preparation, matrix, detection chemistry, and required analytical performance.

Enzymes for Companion Diagnostics (CDx)

Enzymes may support companion diagnostic workflows through nucleic acid amplification, sequencing, target detection, or immunoassay signal generation. Selection must be demonstrated within the specific assay and therapeutic context.

Molecular Infectious Disease Testing Enzymes

Molecular infectious disease workflows use polymerases, reverse transcriptases, nucleases, ligases, strand-displacing enzymes, contamination-control enzymes, and detection components for validated nucleic acid testing formats.

Oncology and Genetic Testing Enzymes

Oncology and genetic testing may use polymerases, reverse transcriptases, ligases, nucleases, and DNA-modifying enzymes for amplification, variant analysis, methylation workflows, and sequencing-library preparation.

Others

This category covers specialized or cross-category applications that do not fit a single standard diagnostic workflow, including emerging analytical formats, research-use assay prototypes, and custom enzyme requirements.

Hydrolases

Hydrolases catalyze bond cleavage through hydrolysis and include proteases, esterases, phosphatases, amidases, and related enzyme classes used in analytical and diagnostic reactions.

Isomerases

Isomerases catalyze intramolecular rearrangements and can support carbohydrate, metabolite, and coupled reaction systems where substrate interconversion is required.

Ligases

Ligases join nucleic acids or other substrates using energy-dependent reactions and are widely used in molecular diagnostic and sequencing workflows.

Lyases

Lyases catalyze bond cleavage or addition without hydrolysis or oxidation-reduction as the primary reaction. They can serve in specialized metabolic and molecular assay systems.

Oxidoreductases

Oxidoreductases catalyze electron-transfer reactions and include dehydrogenases, oxidases, peroxidases, and related enzymes central to optical and electrochemical detection systems.

Transferases

Transferases move functional groups between substrates and include kinases, aminotransferases, glycosyltransferases, and other enzymes used in metabolic and analytical reaction systems.

Polymerase

DNA and RNA polymerases synthesize nucleic acids and are central to PCR, qPCR, sequencing, and other nucleic acid amplification or modification workflows.

Reverse Transcriptases

Reverse transcriptases synthesize complementary DNA from RNA templates and are used in RT-PCR, RT-qPCR, cDNA preparation, and related molecular workflows.

Nucleases, Glycosylases and DNA Repair Enzymes

Nucleases, glycosylases, and DNA repair enzymes modify, remove, process, or repair nucleic acids and support sample preparation, library construction, molecular analysis, and diagnostic workflows.

CRISPR

CRISPR-associated enzymes provide sequence-directed nucleic acid recognition and cleavage and can support CRISPR-based detection and related molecular diagnostic research workflows.

Proteases for Diagnostic Sample Preparation

Proteases can support sample preparation by digesting proteins, reducing matrix complexity, or enabling downstream nucleic acid and analytical workflows. Performance depends on substrate range, conditions, and downstream compatibility.

Creatinine Assay Enzymes & Kits

Creatininase, creatinase, and sarcosine oxidase can form a coupled enzymatic route for creatinine measurement, with peroxide generation used by suitable reporter systems. Assay performance depends on enzyme ratios, specimen interference, calibration, and formulation.

Homocysteine Assay Enzymes & Kits

Enzymatic homocysteine methods can use cycling reactions involving S-adenosylhomocysteine hydrolase, cystathionine synthase or related enzymes, and auxiliary detection components. The selected system should be evaluated as a complete assay.

Sialic Acid Assay Enzymes & Kits

Sialic acid methods can use sialidases, sialic acid aldolase, and related enzymes to release or convert sialic acid for quantitative detection. Product choice depends on the target form and assay pathway.

Triglyceride Assay Enzymes & Kits

Common enzymatic triglyceride methods combine lipase, glycerol kinase, glycerol-3-phosphate oxidase, and a suitable reporter system. Enzyme balance, free glycerol, lipemia, and reagent blank are important development considerations.

Total Cholesterol Assay Enzymes & Kits

Total cholesterol assays commonly combine cholesterol esterase, cholesterol oxidase, and peroxidase or another reporter system. Formulation, solubilization, chromogen stability, and matrix effects should be evaluated together.

Creatine Kinase Assay Enzymes & Kits

Creatine kinase activity methods can couple ATP formation to hexokinase and glucose-6-phosphate dehydrogenase reactions for kinetic measurement. Auxiliary enzymes, substrates, activators, and specimen interference must be matched to the method.

Free Fatty Acid (NEFA) Assay Enzymes & Kits

NEFA assays can use acyl-CoA synthetase and acyl-CoA oxidase in coupled detection systems. Substrate specificity, reaction balance, background signal, and matrix effects are key considerations.

Uric Acid Assay Enzymes & Kits

Uric acid assays commonly use uricase-based oxidation coupled to a suitable signal system. Selection should account for uricase activity, peroxide handling, interfering substances, and assay calibration.

Glucose Assay Enzymes & Kits

Glucose measurement can use glucose oxidase, glucose dehydrogenase, or hexokinase-based reaction systems. The appropriate enzyme depends on oxygen dependence, cofactor requirements, matrix, and detection platform.

Lactate Assay Enzymes & Kits

Lactate assays commonly use lactate oxidase or lactate dehydrogenase with coupled detection chemistry. Enzyme selection should reflect the desired specificity, cofactor system, specimen matrix, and signal format.

Total Bile Acid Assay Enzymes & Kits

Enzymatic total bile acid methods can use 3α-hydroxysteroid dehydrogenase with a cofactor-coupled detection system. Substrate coverage, cofactor balance, calibration, and matrix effects require method-specific evaluation.

Amylase Assay Reagents & Kits

Amylase activity assays use defined substrates and chromogenic or coupled detection systems. Substrate selection, auxiliary enzyme activity, reaction temperature, pH, and calibration all influence measured activity.

HDL/LDL Cholesterol Assay Enzymes & Kits

Homogeneous HDL-C and LDL-C methods combine selective reaction chemistry with cholesterol esterase, cholesterol oxidase, and reporter enzymes. Fraction selectivity and response to atypical lipoproteins should be evaluated during method development.

Enzyme-antibody Conjugates

Enzyme-antibody conjugates combine antibody recognition with enzyme-based signal generation for immunoassay formats such as ELISA, CLIA, and lateral-flow testing. Conjugation strategy should preserve both binding and reporter activity.

HRP/AP and Streptavidin-Enzyme Conjugates

HRP, alkaline phosphatase, and streptavidin-enzyme conjugates support different immunoassay architectures. Selection depends on the recognition reagent, substrate chemistry, incubation conditions, and detection instrument.

Enzyme Substrates and Signal Amplification Components

Substrates convert reporter-enzyme activity into measurable optical or electrochemical signals. Signal-amplification components should be selected with the reporter enzyme, detection range, reaction time, background, and instrument in mind.

Enzyme Stabilizers, Preservatives and Lyophilized Reagent Components

Stabilizers, preservatives, excipients, and drying-compatible components can help maintain enzyme performance during storage and reconstitution. Compatibility must be evaluated against the complete assay formulation and intended storage conditions.

Enzyme Calibrators, Controls and Reference Materials

Calibrators, controls, and reference materials serve different analytical roles. Selection should consider assigned values, matrix, measurement procedure, activity definition, traceability needs, and stability requirements.

Immobilized Enzyme and Magnetic Bead Reagent Components

Immobilized enzymes and magnetic bead components support solid-phase catalysis, capture, separation, and assay automation. Evaluation should include retained activity, accessibility, binding or coupling efficiency, dispersion, washing, and recovery.

PCR/qPCR Enzymes and Master Mixes

Thermostable DNA polymerases, hot-start formats, proofreading enzymes, and master mixes support endpoint PCR, qPCR, multiplexing, and high-fidelity amplification. Selection depends on specificity, processivity, extension performance, and sample matrix.

Reverse Transcription and RT-qPCR Enzymes and Mixes

Reverse transcriptases and one-step or two-step RT-qPCR systems convert RNA to cDNA and support quantitative amplification. Compatibility among the RT enzyme, polymerase, buffer, probes, and thermal profile is essential.

Isothermal Amplification Enzymes and Mixes

Isothermal amplification systems use enzymes with strand-displacement or other specialized activities to amplify nucleic acids at near-constant temperature. Selection depends on the amplification chemistry, target, speed, specificity, and detection format.

NGS Library Preparation Enzymes and Reagents

NGS workflows use enzymes for fragmentation, end repair, A-tailing, phosphorylation, ligation, amplification, and other library-preparation steps. Product choice depends on library architecture, input material, sequencing platform, and workflow compatibility.

CRISPR Diagnostic Enzymes and Reagents

CRISPR-associated enzymes can provide sequence-specific recognition or cleavage for nucleic acid detection. Diagnostic suitability depends on target design, collateral activity where relevant, signal generation, reaction format, and matrix tolerance.

DNA/RNA Ligases and Repair Enzymes

Ligases and repair enzymes modify nucleic acid ends and support joining, end repair, adapter ligation, and related molecular workflows. Selection should match substrate structure, cofactors, temperature, and downstream requirements.

UDG/dUTP Carryover Prevention Enzymes

Uracil-DNA glycosylase with dUTP-based workflows can reduce carryover from uracil-containing amplicons generated in earlier reactions. It is one component of contamination control and does not replace clean workflow practices.

Molecular Sample Preparation Enzymes

Sample-preparation enzymes can support lysis, digestion, nucleic acid release, cleanup, and pretreatment before amplification or analysis. Recovery, inhibitor removal, residual enzyme activity, and downstream compatibility should be assessed together.

Lyophilization-Ready Molecular Diagnostic Reagents

Lyophilization-ready molecular reagents are formulated for drying and reconstitution rather than assuming a liquid formulation will transfer unchanged. Development can evaluate residual moisture, reconstitution, amplification performance, and storage or shipping stability.

Digital PCR-Compatible Enzymes and Premixes

Digital PCR requires reaction chemistry that remains robust after partitioning into droplets, chambers, or other formats. Evaluation may include cluster separation, low-copy performance, partition compatibility, inhibition, and platform-specific materials.